Alzheimer - - onset Alzheimer

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Alzheimer - - onset Alzheimer

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1. alzheimer onset alzheimer

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• "Analysis of the 5-prime sequence, genomic structure, and alternative splicing of the presenilin-1 gene (PSEN1) associated with early onset Alzheimer disease"


• These guarantee onset of early-onset familial Alzheimer disease and all occur in the region of the APP gene that encodes the A domain


• Familial Alzheimer disease is inherited in an autosomal dominant fashion

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